(n): the branch of medicine concerned with the uses, effects, and modes of action of drugs
Xyzagen focuses on select mouse and rat neurology, pain and safety pharmacology models designed to help companies move their early discovery assets forward through focused screening paradigms that can be used to generate useful data for IND candidate selection either as stand-alone studies or in combination with its pharmacokinetic services for PK/PD modeling, or exposure-response comparison.
Xyzagen can also collect blood and tissues for assessment of clinical chemistry/hematology endpoints and histology or immunohistochemistry and our pharmacology models can be integrated into our First-in-Rodent™ PK studies.
We also collaborate with other CROs and Academic Labs in Ophthalmology, Pain and Neurology and thus can manage the design and oversight of your pharmacology program.
Our consultants provide nonclinical CRO vendor qualification, study monitoring and oversight for your nonclinical program.
Oral
Intravenous: infusion/bolus
Subcutaneous
Intraplantar
Intraperitoneal
Blood, plasma, serum
Multiple tissues (brain, liver, spleen…)
CSF, CVF, and Bile via cannulation
These models can be designed with blood collection for assessment of drug exposure. Click on the title to learn more.
ELECTRICAL STIMULATION
CHEMICAL SUBSTANCE
