Single-Dose & Repeat-Dose PK Studies
Generate critical PK insights on clearance, half-life, and accumulation with our single- and repeat-dose studies—guiding dose selection and advancing your program with confidence.
Understanding Drug Behavior Over Time
Xyzagen conducts single-dose and repeat-dose PK studies to evaluate how your compound behaves in vivo. These studies provide essential data on absorption, clearance, and accumulation, supporting dose selection, safety evaluations, and clinical trial planning. Whether at the discovery stage or preparing for IND-enabling studies, our in vivo PK services including single- and repeat-dose PK, deliver the data you need to move forward efficiently.
The Xyzagen Advantage
With Xyzagen, you gain more than a study, you gain a partner committed to making your PK data truly meaningful for development. What sets Xyzagen apart is our ability to move beyond routine PK measurements. Our team brings:
Integrated Study Design
PK, TK, and bioanalysis experts collaborate from the start to ensure your study answers the right questions.
Flexible Dosing Approaches
Single- and repeat-dose designs tailored to your compound, delivery route, and development stage.
Actionable Insights
Data interpretation that goes beyond numbers to guide dose selection, safety strategy, and clinical translation.
Direct Access to Experts
Work closely with senior scientists who apply decades of experience to every study.
Single-Dose Repeat-Dose Study Capabilities
Single-Dose PK Studies
- Characterize absorption, distribution, metabolism, and excretion (ADME)
- Determine half-life, clearance, and bioavailability
- Evaluate multiple administration routes (IV, PO, SC, IM, IP)
- Support lead compound selection and early dose prediction
Repeat-Dose PK/TK Studies
- Assess drug accumulation and steady-state exposure
- Explore multiple dosing schedules over time
- Integrate with toxicokinetic (TK) studies for safety evaluation
- Profile tissue and organ distribution for long-term exposure insights
Time-Course Sampling
- Plasma concentration analysis across defined time points
- High-resolution single- and repeat-dose PK profiles to support translational modeling
Why Choose Xyzagen for In Vivo PK Studies
At Xyzagen, we go beyond routine PK testing. By combining PK and TK expertise with bioanalytical and regulatory insight, we design studies that maximize information yield while minimizing cost and timelines. Our senior scientists ensure your PK data connects directly to downstream development decisions, from dose selection to clinical translation.
Partner with Xyzagen
Ready to advance your program with single-dose PK and repeat-dose PK support? Contact us today to discuss your study needs and see how Xyzagen can help you generate the data required for confident development decisions.
