In Vitro & In Vivo Pharmacology Support
Our integrated in vitro and in vivo pharmacology solutions generate actionable data that informs efficacy, mechanism, and go/no-go decisions early in development.
Comprehensive In Vitro & In Vivo Pharmacology Solutions
Xyzagen provides a full spectrum of in vitro and in vivo pharmacology services that generate actionable data to guide drug development decisions. Our models are designed to assess target engagement, functional activity, and efficacy—helping reduce the risk of late-stage failures while accelerating confident progression from discovery through IND. Our pharmacology support integrates in vitro and in vivo studies to provide a comprehensive understanding of compound behavior, utilizing early discovery data to inform clinical development decisions.
In Vitro Pharmacology & Assay Development
Our in vitro pharmacology capabilities deliver mechanistic and phenotypic insights through high-quality, reproducible assays that define compound potency, selectivity, and cellular activity to inform the development of downstream in vivo studies.
In Vitro Assay Capabilities
In Vivo Efficacy & Translational Models
Our in vivo pharmacology models establish critical PK/PD relationships and dose-response data that drive translational insight. Leveraging well-characterized rodent disease models, we evaluate efficacy, safety, and mechanism of action across multiple therapeutic areas.
In Vivo Capabilities
Why Choose Xyzagen for Pharmacology Support?
Our pharmacology studies leverage Xyzagen’s portfolio of in vivo models across CNS, ocular, inflammatory, and metabolic disease areas, with additional models in active development. Each study integrates bioanalysis and PK modeling to ensure every data point drives meaningful, decision-ready insight.
Our team’s integrated approach connects in vitro and in vivo pharmacology with bioanalysis, PK/PD modeling, and regulatory strategy—delivering a cohesive, end-to-end solution for nonclinical development. From mechanistic understanding to translational validation, Xyzagen ensures your program is built on robust scientific insight
Contact Us
Need customized pharmacology models or study designs? Contact Xyzagen to discuss how our integrated pharmacology solutions can advance your program.
In Vitro & In Vivo Pharmacology Support
Xyzagen offers comprehensive in vitro and in vivo pharmacology solutions tailored to different stages of drug development. Our models help assess target engagement, functional activity, and efficacy while reducing the risk of late-stage failures.
In Vitro Pharmacology Services
We provide mechanistic and functional assays to evaluate receptor binding, enzyme activity, and cellular responses. Our high-throughput screening (HTS) and phenotypic assays allow rapid profiling of lead compounds.
In Vivo Pharmacology Services
Our validated rodent and non-rodent models help establish PK/PD relationships, dose-response curves, and mechanistic insights for drug candidates.
