Neurology & Pain Drug Development Expertise
Neurology and pain represent some of the most challenging therapeutic areas in drug development. The brain and nervous system are highly complex, and drug delivery across the blood–brain barrier or into the central nervous system (CNS) requires specialized knowledge of pharmacology and pharmacokinetics (PK). In pain, measuring outcomes is equally challenging, only relying on behavioral and subjective endpoints that are based on a person’s perception or a nonclinical species’ handling. Our expertise spans a range of neurological and pain indications, where we bring deep scientific insight, regulatory awareness, and practical experience in advancing compounds from preclinical to clinical studies. Our team has been involved in the development, submission and approval of the first-in-class Kv7 channel opener, POTIGA/TROBALT, and the development of novel extended release acute pain medications.
Key Indications We Support
Our Track Record in Neurology & Pain
Our team has supported a diverse portfolio of neurology and pain programs across both small molecules and biologics. This includes:
How We Support Our Clients in Neurology & Pain
We offer tailored solutions that help clients address the unique challenges of neurology and pain drug development, including:
Regulatory Writing
IND/CTD submissions for neurology and pain indications
Preclinical/Nonclinical Project Management
Study design and management of seizure, behavioral, and pain models
Translational Pharmacology
Applying preclinical findings to optimize early clinical trial design
Why PK Matters in Neurology & Pain
Did You Know?
- Blood–brain barrier permeability strongly impacts CNS drug delivery and requires tailored PK strategies.
- CNS drug clearance pathways can differ from systemic drugs, requiring specialized analysis.
- Pain endpoints are often subjective; integrating PK/PD can strengthen clinical trial design and reduce regulatory risk.
Next Steps
Talk to us about how PK and translational pharmacology can de-risk your Neurology or Pain program. Learn more about our related services in pharmacology models, PK/PD, and clinical pharmacology on our Solutions page—or reach out to our team directly.
