Safety & Non-GLP Toxicology
Early non-GLP toxicology studies designed to identify potential safety risks, accelerate decision-making, and support confident advancement to GLP studies.
Comprehensive Non-GLP Safety & Toxicology Services
Early toxicology assessments are critical for identifying potential adverse effects and guiding strategic decisions in drug development. Xyzagen provides non-GLP safety pharmacology and toxicology screening to evaluate compound tolerability, organ-specific toxicity, and functional safety—helping you de-risk programs before initiating GLP or regulatory studies.
Non-GLP Toxicology Capabilities
Our flexible and rapid non-GLP platform supports a range of studies to evaluate safety and organ-specific toxicity. Representative capabilities include:
Acute & Subacute Toxicity:
Single- and repeat-dose studies in rodents
Hematology & Clinical Chemistry:
Biomarker and toxicity assessments
Respiratory & CNS Safety:
CFA-induced arthritis, Carrageenan models
Histopathology & Organ-Specific Toxicity:
Liver, kidney, GI, immune toxicity
Applications Across Drug Development
These studies provide early insight into potential adverse effects, support lead optimization, and help prioritize compounds with favorable safety profiles. By identifying risks early, Xyzagen enables smarter progression to GLP toxicology, IND-enabling studies, and first-in-human trials.
Representative Non-
GLP Toxicology Studies
Xyzagen’s non-GLP toxicology platform includes a broad range of studies to assess safety across organ systems and functional endpoints. Representative studies include:
Acute & Subacute Toxicity
- Single-dose rodent
- Repeat-dose rodent
Respiratory & CNS Safety
- Respiratory rate
- Behavioral assessment
- Motor function evaluation
Hematology & Clinical Chemistry
- Blood biomarkers
- Liver function
- Kidney function
Applications & Custom Models
- Rapid toxicity screens
- Lead optimization
- Custom organ-specific assays
Why Choose Xyzagen for Early Toxicology?
Xyzagen combines toxicology expertise with pharmacology, PK/PD modeling, and flexible study design. Our team delivers high-quality, actionable data with rapid turnaround—helping clients make informed decisions, reduce late-stage attrition, and accelerate program timelines.
Contact Us
Explore early toxicology solutions for your program. Contact Xyzagen to discuss a tailored study plan.
