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What Are Bioanalytical Services?

Bioanalytical services involve the quantitative measurement of drugs, metabolites, and biomarkers in biological matrices to support nonclinical and clinical development. These data inform critical assessments of pharmacokinetics (PK), toxicokinetics (TK), immunogenicity, and efficacy.

Bioanalytical Laboratory Services at Xyzagen

Xyzagen combines scientific precision with operational agility, offering tailored solutions for early-stage bioanalysis. Our wet lab capabilities and First-in-Rodent® platforms accelerate decision-making while ensuring data integrity and quality. We provide expert scientific guidance for method development, assay transfer, and vendor oversight—so your program moves forward with confidence.

The Xyzagen Advantage

1.

Custom bioanalytical strategies tailored to your compound

2.

Integrated support for method development and validation

3.

Expert scientists with decades of experience in PK/TK analysis

4.

Rapid turnaround with scalable workflows for in-house bioanalytical support on our equipment

Core Bioanalytical Capabilities

Small Molecule Bioanalysis

Xyzagen uses LC-MS/MS and ELISA based approaches for sensitive quantification of small molecules in plasma, serum, urine, tissue, and other biological matrices. We support both regulated and nonGLP bioanalysis to inform development from early discovery through IND-enabling studies.

  • Quantification of small molecules, peptides, proteins, and oligonucleotides
  • Discovery to Qualified methods for nonGLP bioanalysis
  • Assay transfer and method validation support for GLP studies
Large Molecule Bioanalysis

Xyzagen supports large molecule bioanalysis through specialized assays and technologies for biologics, biosimilars, and complex modalities. Our platforms enable the accurate quantification of therapeutic proteins, antibody-drug conjugates (ADCs), and other biologics across a range of matrices.

  • Quantification of monoclonal antibodies, ADCs, and fusion proteins
  • Hybrid LBA-LC/MS/MS assays for complex molecules
  • Assay support for early-phase immunogenicity studies
  • High-throughput platforms for large molecule PK analysis
Metabolite Identification

Understanding the metabolic fate of a compound is essential for selecting the appropriate toxicology species and ensuring translatability to human metabolite identification.

  • Identification of major metabolites
  • Metabolic profiling
  • Support for DMPK and toxicology program
GLP Method Transfer, Validation, Oversight, and Vendor Management

Xyzagen offers comprehensive support for transferring and validating methods within their third-party vendor oversight program.

  • Assay transfer from nonGLP to GLP settings
  • Vendor selection and qualification for GLP method validation
  • Oversight and coordination of GLP validation activities
  • Data review and scientific input throughout the validation lifecycle

Why Choose Xyzagen for Bioanalytical Services?

Xyzagen brings together scientific depth and operational efficiency to support rapid, reliable bioanalytical testing in early development. Our discovery-stage focus, integrated nonclinical services, and First-in-Rodent® platforms allow us to move quickly—without sacrificing scientific rigor. Whether you’re optimizing a lead candidate or preparing for IND, our team provides hands-on expertise, seamless study coordination, and the analytical precision needed to generate actionable data.

Contact Us

Contact us today to explore how our bioanalytical services can support your development program.

Schedule a Consultation